The high dose … A new vaccine called Fluzone High-Dose Quadrivalent that is made up of four flu strains has been approved for people age 65 and older. Fluzone (IIV4) 0.5 mL (single-dose syringe) 0 6 months & older3 150 90686 0.5 mL (single-dose vial) 0 6 months & older3 150 90686 5.0 mL (multi-dose vial) 25 6 through 35 months3 158 90687 5.0 mL (multi-dose vial) 25 3 years & older 158 90688 Fluzone High-Dose (IIV4-HD) 0.7 mL (single-dose syringe) 0 65 … Currently in the U.S., two influenza vaccines are licensed exclusively for use in seniors: an egg-grown trivalent inactivated high dose (HD-IIV3) influenza vaccine (Fluzone® High-Dose, Sanofi Pasteur) and an egg-grown trivalent inactivated adjuvanted (aIIV3) influenza vaccine (Fluad®, Seqirus). You can get both the high-dose and adjuvanted flu vaccines at your doctor's office, but you can also find the high dose … The high-dose vaccines, however, contain four times as much flu virus antigen — the part of the vaccine that stimulates the immune system — as regular Fluzone … The HD-IIV4 replaces Fluzone High-Dose (trivalent). 2009-10 (H1N1pdm09; not contained in HD … Fluzone High-Dose Quadrivalent (HD-IIV4, Sanofi Pasteur) and Fluad Quadrivalent (Seqirus), both for adults 65 years and older, are new for 2020–21. Blood will be sampled pre- and post-vaccine … § RCT, double-blind ≥65 years: 6,107 HD-IIV3 3,051 SD-IIV3. HD … HD-IIV3 (Fluzone High-Dose, Sanofi Pasteur) SD-IIV3 (Fluzone)DiazGranadosCA et al, Vaccine 2013;31:861-66. Fluzone High-Dose is indicated for active immunization of persons 65 years of age and older against influenza disease caused by influenza virus subtypes A and type B contained in the vaccine. Fluzone is specifically approved for the … We estimated the relative vaccine effectiveness (rVE) of a trivalent high dose (HD … Results from a clinical trial of more than 30,000 participants showed that adults 65 years and older who received the high dose vaccine had 24% fewer influenza illnesses as compared to those who received the standard dose flu vaccine. ACIP’s flu vaccine recommnedations for 2020-21 were updated to outline the composition of this year’s vaccines, as well as two newly licensed influenza vaccines—Fluzone High-Dose Quadrivalent and Fluad Quadrivalent—for patients ≥65 … Fluzone high-dose (HD) is an inactivated influenza vaccine, formulated to contain four times the antigen content of the standard dose (SD) vaccine. Background: Adults 65 years and older (seniors) experience more complications following influenza infection than younger adults. There are two types of vaccines that the CDC recommends for people over 65: the high dose flu vaccine, also called Fluzone, and the adjuvanted flu vaccine, known as Fluad. ... Age 65 and older to receive either Fluad or HD vaccine at 1:1 ratio. FLUAD vs. FLUZONE HD Influenza Vaccine in Residents of Long Term Care.